HISTOPATHOLOGICAL FINDINGS IN CLINICALLY DIAGNOSED ACUTE APPENDICITIS PATIENTS IN TERTIARY CARE HOSPITAL OF PESHAWAR.

http://doi.org/10.46536/jpumhs/2023/13.03.450

Abstract

OBJECTIVE: To find out unexpected histopathology in patient undergoing appendectomy for clinically

diagnosed appendicitis and to determine the frequency of biopsy proven appendicitis in patient undergoing

appendectomy for clinically diagnosed appendicitis. STUDY DESIGN: Retrospective Cross-sectional

study. PLACE AND DURATION OF STUDY: Allied teaching hospitals of PMC and histopathology lab

PMC, From June 2018 to December 202. METHODOLOGY: 440 patients who met our inclusion criteria

and were selected using non probability convenient sampling. Patients of all age groups and both genders

were included in our study. Patients in whom appendectomy was performed as part of other abdominal

procedure were excluded. RESULTS: The mean age group of our study participants was 25.3+- 13.6 years.

Majority of patients undergoing appendectomies were of age group 11 to 20 43.8%. Male were 56.1% and

43.9% were female. Most of our patients’ histopathological examination findings were consistent with acute

appendicitis 55%. Negative appendectomies were performed on 4.1% patients. The overall usual findings

were found in 84.6% patients. While unexpected findings were found in 11.3% patients. CONCLUSION:

The unexpected findings detected by chance in our study were 11.3 %. Among those cases, serious

pathologies like carcinoma were very low 0.4% and there were no significant change in the management

of those pathologies. Routine histopathology is expensive and constitutes workload on pathologist and

financial burden on patients. So only those specimens should be subjected to biopsy which shows gross

evidence of any sinister pathology.