COMPARISON OF OUTCOME OF 0.5% HYPERBARIC BUPIVACAINE WITH 0.5% HYPERBARIC ROPIVACAINE IN SPINAL ANAESTHESIA FOR PERIANAL SURGERIES.

http://doi.org/10.46536/jpumhs/2023/13.01.392

Abstract

Abstract

Introduction: The field of anaesthesiology has undergone significant advancements in recent

years, resulting in improved patient outcomes and reduced hospitalization durations. This is

primarily due to the availability of anaesthetic agents that block sensations locally or regionally

for shorter durations. Objective: To compare the outcome of 0.5% hyperbaric Ropivacaine with

0.5% hyperbaric Bupivacaine in spinal anaesthesia for perianal surgeries. Design: Randomized

controlled trial. Setting: Anaesthesiology Department, Surgical Intensive Care Unit And Pain

Management, Jinnah Post graduate Medical Centre (JPMC), Karachi. Duration: Six months

(From 7 April 2016 to 7 October 2016). Methods: 126 Perianal surgery patients were

approached for consent for study. Two groups viz; A & B were made, and group allocation of

consecutive patients were made through using opaque envelopes containing strip of either group.

Group A patients received three mililiter of Ropivacaine (5 mg/ml) with glucose 83 mg/ml.

Whereas, Group B received three mililiter of hyperbaric Bupivacaine (5 mg/ml) with glucose 80

mg/ml. Moreover, Oral temazepam 10–20 mg was administered to patients before to surgery to

reduce anxiety. Results: The duration of sensory block was statistically less in the Ropivacaine

group (153.8±9.3min) as compared to Bupivacaine group (190.2±8.3min) with P-value 0.0001.

In addition, the ropivacaine group's mean time in motor block was less than that of the

bupivacaine group (120.89±12.122 min vs 189.33±11.947min; P = 0.0001). Conclusion:

According to the results of the current investigation, bupivacaine applied intrathecally causes

sensory block to begin more quickly and last longer than ropivacaine.