Response of Combined Antiviral Therapy in Chronic HCV Infection in Interior of Sindh
Abstract
To observe the treatment response and sustained response with combined antiviral therapy in patients ofchronic hepatitis C in interior of Sindh.
Design: A prospective cross-sectional, observational study carried out from August 2006 to Dec. 2009. Setting: Research Medical Center LUMHS Jamshoro, Departments of Pathology. Peoples Medical College Nawabshah and Department of Biotechnology University of Karachi.
Patients: A total of 344 HCV-PCR positive patients with persistent abnormal alanine aminotrasferase levels and histological evidence of chronic hepatitis with either fibrosis or inflammatory activity by biopsy were evaluated 239 men and 105 women with ages between 18-55 years of age were included in the study.