Uric Acid & CRF: Assessment of Serum Uric Acid level in Patients with Chronic Renal Failure in PMCH Nawabshah, a tertiary care hospital.

Abstract

Background: Increased uric acid levels affect the prognosis and the disease outcome in CRF (chronic renal failure)

patients.

Objective: The present research was aimed to observe connection among CKD & increased uric acid levels.

Material & Methods:

Design: Current research was cross sectional study.

Place: Carried at PMCH Nawabshah.

Duration: From 1" January 2017 to 30‘June 2018.

Subjects: Our study included patients with CKD visiting the haemodialysis department and the serum uric acid levels were checked in all subjects.

Results: In current study 168 subjects were included. Subjects were known CKD patients and presented with high serum

creatinine levels. Out of these, 125 were male while 43 were female subjects.

Mean age of subjects was 45.82 SD+12.91 years. The mean serum uric acid was 7.75 SD+1.49 mg/dl. Mean levels of serum creatinine were 5.15 SD+3.55 mg/dl. Normal uric acid levels were detected in 41(32.89c) males and 12 (27.99c) females. Abnormal uric acid levels were present in 84 (67.29c) males and 31(72.1to) females. Normal creatinine level was present in 5 males and 01 female. Abnormal creatinine levels were present in 120 males and 42 females.

Conclusion: Increased levels of serum uric acid commonly seen in subjects with chronic renal failure, additional researches are required to assess the link between CKD prognosisand outcome with hyperuricemia as an essential part for the management of CKD.