Myoinositol Potential against Polycystic Ovary Syndrome (PCOS) in Diabetic Patients

Abstract

Objective: To find the potential of myoinositol extract from beans against PCOS in obese diabetic females. Methods: This experimental research work was performed during October 2017 to March 2018, in industrial biotechnology research lab of biochemistry in Government College University Faisalabad, 30 obese diagnosed females of type-2 diabetes mellitus (T2DM) with PCOS, having age >30 years and BMI>1.18 kg/m2were selected in accordance to convenient sampling technique from Independent University Hospital Faisalabad. A physical examination, medical history and informed consent were recorded. The subjects were divided into 2 groups, one treatment group (15 subjects, taking myoinositol extract dose 2g/twice a day) and other placebo group (15 subjects). Results: Thirty diabetic PCOS subjects with mean age 35.96±2.13 years and BMI 25.84± 1.81kg/m2 were included., fasting blood glucose level (123±3.17mg/d1) and HbA,C level (6±0A1%) significantly reduce (p<0.05) as compared to control. No significant difference was observed in CBC and BMI (p>0.05). Moreover, MI dosage (2g/day) indicated no side effects. Conclusion: HbA,C and fasting blood glucose level was significantly decrease in diabetic PCOS subjects when treated with MI for three months. MI dosage 2g/twice a day indicated no side effect e.g diarrhea, nausea, and flatus