trects of Papaya Seed on Quantitative Total Leukocyte & Differential Cell Counts in Rabbits

Abstract

Objective: To observe the effects of papaya seeds on quantitative total white blood cells and differential counts. Methods: This experimental study was conducted at Pharmacology Department, Peoples University of Medical and Health Sciences foe women. Nawabshah from Oct to Dec 2017, thirty adult and healthy female rabbits were selected and divided equally into two groups, Group A (Control) given only fresh hay & water and Group B (treated) given papaya seeds powder as dose of 500mg once a day for 60 days along with fresh hay & v ,ter provided ad libitum, then blood samples were sent to Diagnostic & Research Laboratory PUMHSW, fbr assessment of total leukocytes and differential cell counts. Results: Total leukocyte count raised, highest (18.78%) increase seen on Day-30 in Group-B (treated), Lymphocytes increased significantly with (p<0.05) in comparison to the control group on day-3o&45. Neutrophi I count remained in the normal range in Group-B, Eosinophils count decreased with (p<0.05) on Day-30. Whereas Monocytes count decreased from 3.1±0.36 to 1.8+0.17 in group-B. Conclusion: An increment was seen in total leukocyte count due to increased lymphocyte count. Neutrophils remained within normal limits, whereas eosinophils & monocytes decreased.