AN ASSESSMENT OF FETO-MATERNAL OUTCOME IN PREGNANT WOMEN WITH HYPERTHYROIDISM.

J Peop Univ Med Health Sci. 2025:15(3), 124-131. http://doi.org/10.46536/jpumhs/2025/15.03.667

Abstract

BACKGROUND: Adequate levels of the thyroid hormone are very important for a healthy
pregnancy, normal growth of the fetus and maturation, while untreated thyroid issues are
associated to several complications affecting both maternal outcomes and growth of a child.
OBJECTIVE: To evaluate the fetal and maternal outcomes among pregnant women presented with
hyperthyroidism. METHODS: This prospective cross-sectional study was conducted at Obstetrics
and Gynecology department of Bahawal Victoria Hospital, Bahawalpur, from September 2024 to
February 2025. All the women during pregnancy, aged 18 to 40 years presented with pre-existing or
the gestational hyperthyroidism of either parity were included. The outcomes of the pregnancy
including pre-eclampsia, abruptio placentae, gestational diabetes, c-section, and postpartum thyroiditis
were evaluated through detailed reviews of medical records, clinical assessments, and laboratory
findings, concentrating the frequency and severity of complications. The data was entered and
analyzed using SPSS version 26. RESULTS: Overall average age of women was 31.62 years.
Maternal outcomes noted as 20.8% preeclampsia, 15.2% GDM, 4% abruptio placenta, followed by
increased rate of cesarean deliveries at 41.6% and postpartum hemorrhage 12.8%. Additionally, the
fetal outcomes were assessed as preterm births 30%, and low birth weight babies 25%. Though, no
statistically significant impact was found of maternal age, gestational age, or parity on feto- maternal
outcomes (p = > 0.05). CONCLUSIONS: The hyperthyroidism during pregnancy observed to be a
significant clinical concern and contributor to adverse feto-maternal outcomes. Consequently, the
early diagnosis, careful monitoring, and individualized management is very important, for better feto
maternal outcome.