IMPACT OF ACUTE KIDNEY INJURY ON CARDIAC FUNCTION: AN ANALYSIS OF MORTALITY RISK IN CRITICAL CARE PATIENTS.

JPUMHS;2024:14:03,90-95.http://doi.org/10.46536/jpumhs/2024/14.03.539

Abstract

BACKGROUND:Acute Kidney Injury usually aggravates cardiac vascular complications, therefore aggravating mortality in critically ill patients. Co-morbid conditions such as diabetes mellitus, hypertension, IHD, CCF, CKD, obesity, and old age in the presence of AKI significantly influence cardiac outcomes. OBJECTIVE:To evaluate the impact of AKI on cardiac function and predict risk for death by applying specific cardiovascular risk factors. METHODS:There were 386 patients diagnosed with AKI, grouped into as 20–40 years, 40–60 years, >60 years and gender male, 58%; female, 42%. The mortality by demographics and co-morbidities has been studied for their associations with cardiac outcomes. RESULTS:The mean ages were 43.22 years with SD± 12.61 years, mean creatinine levels were 3.59 mg/dl with SD± 0.61 mg/dl. Mortality was at a peak among the aged people >60 being at 43%, followed by those in middle age groups that were 25% and in young age being 12% but was marked with the occurrence of obesity which was significant. The rates among men were found to be higher at 35% compared to women at 28%. CONCLUSION:The study unravels the fact that AKI carries a compounded mortality risk for cardiac function, but a great emphasis was given to the necessity of developing targeted management strategies to address high-risk conditions, especially in older, male, and co morbid AKI patients. Proper monitoring would enable early intervention, thus improving survival in this population.